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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UBE3B All Species: 17.27
Human Site: S369 Identified Species: 29.23
UniProt: Q7Z3V4 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7Z3V4 NP_569733.2 1068 123070 S369 V L G W F S Q S V D Y G L N E
Chimpanzee Pan troglodytes XP_509354 1068 122921 S369 V L G W F S Q S V D Y G L N E
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_543437 1068 123121 S369 V L G W F S Q S V D Y G L N E
Cat Felis silvestris
Mouse Mus musculus Q9ES34 1070 122743 P369 V L G W F S Q P V D Y G L N D
Rat Rattus norvegicus NP_001137366 1070 122598 S369 V L G W F S Q S V D Y G L N D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_423951 837 96057 Q210 K G F Y S V L Q I L L T N G L
Frog Xenopus laevis Q6DCL5 944 106566 E314 L S I S S S Y E A Q M K S L L
Zebra Danio Brachydanio rerio A9JRZ0 765 87445 S138 Q I V V S L Q S R D R I G S G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VVI3 1007 114856 T348 S A P P N T P T N N N G I L A
Honey Bee Apis mellifera XP_392283 1063 121439 K370 I L G W L A Q K V D T S L Q E
Nematode Worm Caenorhab. elegans NP_499392 1066 120863 Y359 W H P V F G H Y L L P I D K R
Sea Urchin Strong. purpuratus XP_786887 582 66877
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RWB8 1029 117643 F359 I A L V A T F F L E T L P P V
Baker's Yeast Sacchar. cerevisiae P53119 910 105547 A283 D E V I A T T A N Y V S D E D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.2 N.A. 96.5 N.A. 92.1 91.8 N.A. N.A. 68.6 20.8 22.8 N.A. 20.4 51.5 37.6 37.1
Protein Similarity: 100 98.9 N.A. 98.5 N.A. 96 96.1 N.A. N.A. 74 40.1 38.4 N.A. 37.1 69.1 58.4 44.9
P-Site Identity: 100 100 N.A. 100 N.A. 86.6 93.3 N.A. N.A. 0 6.6 20 N.A. 6.6 53.3 6.6 0
P-Site Similarity: 100 100 N.A. 100 N.A. 93.3 100 N.A. N.A. 13.3 13.3 33.3 N.A. 33.3 66.6 13.3 0
Percent
Protein Identity: N.A. N.A. N.A. 28.7 25.1 N.A.
Protein Similarity: N.A. N.A. N.A. 48.7 42 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 15 0 0 15 8 0 8 8 0 0 0 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 0 0 0 0 50 0 0 15 0 22 % D
% Glu: 0 8 0 0 0 0 0 8 0 8 0 0 0 8 29 % E
% Phe: 0 0 8 0 43 0 8 8 0 0 0 0 0 0 0 % F
% Gly: 0 8 43 0 0 8 0 0 0 0 0 43 8 8 8 % G
% His: 0 8 0 0 0 0 8 0 0 0 0 0 0 0 0 % H
% Ile: 15 8 8 8 0 0 0 0 8 0 0 15 8 0 0 % I
% Lys: 8 0 0 0 0 0 0 8 0 0 0 8 0 8 0 % K
% Leu: 8 43 8 0 8 8 8 0 15 15 8 8 43 15 15 % L
% Met: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % M
% Asn: 0 0 0 0 8 0 0 0 15 8 8 0 8 36 0 % N
% Pro: 0 0 15 8 0 0 8 8 0 0 8 0 8 8 0 % P
% Gln: 8 0 0 0 0 0 50 8 0 8 0 0 0 8 0 % Q
% Arg: 0 0 0 0 0 0 0 0 8 0 8 0 0 0 8 % R
% Ser: 8 8 0 8 22 43 0 36 0 0 0 15 8 8 0 % S
% Thr: 0 0 0 0 0 22 8 8 0 0 15 8 0 0 0 % T
% Val: 36 0 15 22 0 8 0 0 43 0 8 0 0 0 8 % V
% Trp: 8 0 0 43 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 8 8 0 8 36 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _